Coenzyme Q10 — commonly written as CoQ10 — is a fat-soluble compound present in virtually every cell in the human body. It plays a central role in the mitochondrial electron transport chain, the process cells use to generate ATP (adenosine triphosphate), the body's primary energy currency. CoQ10 also functions as an antioxidant within cell membranes, where it neutralises free radicals.
Two forms: ubiquinone and ubiquinol
CoQ10 exists in two interconvertible forms. Ubiquinone is the oxidised form — the version found in most traditional CoQ10 supplements. Ubiquinol is the reduced, active antioxidant form. The body naturally converts ubiquinone to ubiquinol, and research suggests this conversion may become less efficient with age. For this reason, some manufacturers now sell ubiquinol directly as a supplement, arguing it requires fewer conversion steps.
Clinical trials comparing the two forms show that ubiquinol tends to produce higher blood plasma levels at equivalent doses, particularly in older individuals. However, both forms raise CoQ10 levels in the blood, and ubiquinone remains the form used in the majority of published studies.
How CoQ10 is absorbed
CoQ10 is fat-soluble, meaning absorption is significantly improved when taken with a meal containing fat. Some formulations use softgels with oil carriers or emulsification technology to improve bioavailability. Doses used in research range widely — from 100 mg to 600 mg per day — and the optimal dose depends on the intended purpose and individual factors.
What the research covers
CoQ10 has been studied in the context of cardiovascular physiology, statin use (statins reduce endogenous CoQ10 synthesis), fertility research, and neurological ageing. It is also used by athletes for its theoretical role in mitochondrial energy production. The evidence is strongest for its use in individuals taking statins, where CoQ10 levels in muscle tissue may be reduced as a side effect of the medication.
Dietary sources
CoQ10 is found naturally in organ meats (particularly heart and liver), fatty fish, beef, and to a lesser extent in nuts, seeds, and vegetables. Dietary intake is typically low — supplemental doses in research studies are almost always higher than what can be obtained from food alone.
CoQ10 available in Lebanon
Supplements & More carries CoQ10 supplements imported from the United States, available with cash on delivery across all regions of Lebanon.